Drug-Induced Parkinsonism

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Drug-Induced Parkinsonism

Drug-induced parkinsonism (DIP) is the second-most-common etiology of parkinsonism in the elderly after Parkinson's disease (PD). Many patients with DIP may be misdiagnosed with PD because the clinical features of these two conditions are indistinguishable. Moreover, neurological deficits in patients with DIP may be severe enough to affect daily activities and may persist for long periods of ti...

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Drug Induced Parkinsonism

Since 1947 a number of chemists who used MPTP for legitimate purposes developed Parkinsonism. Final recognition that MPTP induces Parkinsonism came in 1982 when a batch of an illicit narcotic (MPPP) became contaminated to form MPTP and a group of users demonstrated profoundly disabling Parkinsonism. Parkinson’s is a progressive neurological condition, which is characterised by both motor (movem...

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Drug Induced Parkinsonism: An Overview

For more than half a century, drug induced Parkinsonism (DIP) has captured the attention of the physicians and researchers alike. More and more drugs underwent extensive scrutiny and causal agents were penned down from notorious antipsychotics [1] to more innocent anti-arrhythmic agents [2]. Earlier studies kept DIP as commonest cause of secondary Parkinsonism and the second commonest cause of ...

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E. C. T. and Drug Induced Parkinsonism

A cross-sectional evaluation of the presence of drug induced parkinsonian symptoms in hospitalized patients was done. Patients who had received two or more ECTs had lower scores of parkinsonism when compared to those who were net receiving ECT. Since the patient groups were comparable on parameters which would influence the occurrence and development of drug induced parkinsonism, the lowered sc...

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Visual contrast sensitivity in drug-induced Parkinsonism.

The influence of stimulus orientation on contrast sensitivity function was studied in 10 patients with drug-induced Parkinsonism. Nine of the 10 patients had at least one eye with contrast sensitivity deficit for vertical and/or horizontal stimuli. Only generalised contrast sensitivity loss, observed in two eyes, was stimulus orientation independent. All spatial frequency-selective contrast def...

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ژورنال

عنوان ژورنال: Journal of Clinical Neurology

سال: 2012

ISSN: 1738-6586,2005-5013

DOI: 10.3988/jcn.2012.8.1.15